Why Zebras Don't Get Ulcers

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A Guide to Stress, Stress-Related Diseases, and Coping

Combining cutting edge research with a healthy dose of humor and practical advice, Sapolsky explains how prolonged stress causes or intensifies mental afflictions.

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March 26,2025
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This book is a good introduction to stress and its effects on physiology and psychology (Nicola's area of expertise). Although it is written for a lay audience, I often got the feeling it was written for a lay audience of primarily MDs.

By the end of the book, you will feel like you and epinephrine, norepinephrine, and glucocorticoids are all old friends--but in spite of the terminology, it is really an easy read and full of good humor and interesting anecdotes (e.g. hyenas are very peculiar).

Here is a quote, taken out of context, that I enjoyed:
"Every child cannot grow up to be president; it turned out that merely by holding hands and singing folk songs we couldn't end all war, and hunger does not disappear just by visualizing a world without it....Would that it were so. And shame on those who would sell this view."

You may not like all of his opinions. Sapolsky is an unapologetic atheist, but appears to have a high opinion of many religious people. He also speaks frankly about sex. He also believes in animal testing, although he thinks that some past tests went too far.
March 26,2025
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I'm a major stresser.

I stress over big things, over little things, over all things. Because I'm a stresser, I'm all too often a stressor (i.e. a person or thing that causes stress) for the people around me.

It sucks, really. I don't like stressing, something that all those who are constantly telling me to "calm down," "chill out," "relax!" just don't seem to get.

It's not like I can just flip a switch here.

If only!

It worries me, because of course, along with stressing, I'm also anxious. Yes, anxiety is a constant companion. I worry all the time that I don't have enough time, so I spend all my time worrying.

Time, money, people ... these are the main things that cause me stress and anxiety, but they certainly aren't the only ones.

I worry because I stress. Mainly because, if I get so stressed going to the grocery story (and I very much do), how will I handle something truly monumental? Like, say, the death of a loved one, or bad health news? (I have, for now, been incredibly fortunate to not to have had to deal with either.)

My stress sometimes starts off over small things, not emailing a friend who emailed me a month ago, say, forgetting to pick up toothpaste, and then spirals into greater stresses, what I call "tomorrow stresses" (though my stress is happening very much in the present moment).

I don't have health insurance, so what if something happens to me and I need to go the doctor? What if I can't pay my rent? What if I am forced forced to work in an office again? (god forbid!)

I very much have tried/am trying to get my anxiety/stress under control. No, I won't take anxiety medication. I flat out refuse to even consider the prospect of anti-depressants or the like (I'm not really depressed anyway ... I don't think). I've always viewed pills as the worst sort of coping mechanism (well, aside from harder drugs like alcohol or heroin, that is). Always having to constantly up the dosage to maintain the same feeling of ... numbness. No thanks.

No disrespect intended to anyone who takes prescription meds, by the way. Whatever you need to get you through the day. I just know that it's not something I can envision for myself ...

So I've tried other things.

I've downloaded a meditation app and one of these days — tomorrow, let's say, as I do every day — I will actually start it. I bought and read this book, which I otherwise wouldn't have done.

It's a very good book. I liked it a lot and I'm glad I read it. Boiling down stress to various chemical elements, leading to an over abundance of glucocorticoids, leading to umm, bad things, helps ... I think. It takes the emotional component out of it, makes it feel more mechanical, like a broken chain on a bicycle that can, maybe, be fixed.

Some might complain that of the 18 chapters that make up "Why Zebras Don't Get Ulcers," only the final one, "Managing Stress," actually tells you how to, uh, manage stress. But those 17 former chapters are equally as important.

For one thing, they give you a better idea of the effects of stressing out (spoiler: they're not good), which was, yes, stressful to learn about. But for another, the cumulative effect of all the various stressors, of learning the hows and the whys of it all, is oddly comforting.

Many would likely consider a book about stress a particularly timely read, in light of, well, the times. Which is a funny thing, because I've found — pathologically? — that I'm possibly less stressed now than I was before. In some way, it again goes back to the idea of time, of missing out on life, on things. Misery does love company, and the fact that so many people are, sadly, miserable at the current moment — isolated in their homes, unable to attend any sort of gatherings or events as they've all been canceled — comforts me as I know that 1. I'm not alone and 2. I'm not missing out on anything.

Yes, maybe I'm a villain ripped straight from a comic book. At least credit me for my honesty.

And that's the one aspect I wish Robert Sapolsky — who I feel I'd very much like as a person — had covered, albeit my edition (the third, released in 2004) may have been slightly too old for that, Millennial that I am.

Which is whether there is any truth to the idea that anxiety and stress may be not just individual, but generational as well. You often hear, or at least I do, that Millennials are more prone to stress, more anxious, than their generational predecessors. There are, of course, many very reasonable explanations for this.

Student debt. Gross inequality. Global warming. Helicopter parenting. Stricter moral upbringings. Growing up in the age of global terrorism. General disenchantment with modern politics. Untempered capitalism. Doubts as to whether one can truly make a difference, etc etc etc, ad infinitum.

Because when I talk to my Millennial counterparts, I don't feel unique in my anxiety, in my stress over how to survive, how to make a living, in 2020. Nobody seems to have the answers, and the general advice from our elders seems to be "don't worry so much" when indeed there seems to be so much to worry about.

It's an anxiety stemming not from a fear of nonexistence, of our mortality, but of existence itself, of reconciling with the fact that a human existence bears no more meaning than an animal one, because we are, after all, just animals.

We struggle to reconcile with this fact, to cope with the reality that there is no meaning to any of it.

The only answer, then, is to make our own meaning. To find it in books, in relationships, in writing, in forms of expression that will outlast ourselves.

You may even find it here.
March 26,2025
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A list of qualifications as long as your arm but in the one section I bothered to read he sounded like a charlatan. He still maintains that stress causes ulcers when we know that a bacteria does. He even describes how this amazing discovery came about but he still goes down the stress path.
March 26,2025
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The author is really good at making confusing biological concepts accessible to the reader. Also I think chapter 17 on the relationship between low socioeconomic status and poor health outcomes should be required reading for everyone. Because some of y’all still don’t get it!
March 26,2025
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Well researched book. Sapolsky, who I am a big fan of, explains why certain types of stresses like long work days end up having more serious negative effects on your physiology than do other types of stress such as a lion chasing after you. Sure the lion stresses you out then and there but a week from now your bodily functions won't still be affected by it.

My one beef with this book is that it doesn't give you much in the way of how to handle stress. I felt somewhat more stressed after reading reading this book because I finally had a good understanding of all of its negative effects but still didn't know what to do about it....
March 26,2025
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This is a great book (with a shed load of references to boot) about what stress is, how it works and how it's caused. Others have complained that this book has a relatively short section on "Managing Stress" for a book that claims to be a "Guide to Stress". I believe that decent understanding of the condition effecting me is the best step I can take towards self healing, and as such I find this book extremely useful and brimming with knowledge I can apply in my own stressful life. This may not be the case for everyone so take my praise with a grain of salt.

The writing style is very academic, it's written to inform and is structured so it's easy to skim and find the content that's relevant to you. Most of the book can be skimmed, I'd suggest looking at topic sentences and reading a paragraph only if the topic seems surprising or interesting—reading this cover-to-cover would be a bore unless you had an existing interest in biology, psychology and neurology all at once.

How stress interacts with existing mental conditions, such as depression and anxiety, is also covered in great detail giving a very down-to-earth explain-like-I'm-five description of how they're triggered in the brain. Requires you to remeber a few complex chemical names like 'glucocorticoids' and 'beta-endorphins' but is pretty accessible once you grasp the meanings of these.

Recommended for anyone who wants to understand more about their mental health, why they get so stressed all the time and why stress need to be seriously dealt with.
March 26,2025
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Difficile ma ne vale la pena, tutto quello che devi sapere sullo stress... quello vero.
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