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Big rhetorical question: So why is this book called The Seven Daughters of Eve? The second-to-last chapter clearly reveals that there are thirty-three ancestral mothers in total. The "seven" refers to Europeans only... what's up with being so misleading, Sykes? He never addresses the distinction, either, just casually drops the information at the back of the book, behind the seven annoying subjective chapters like he hopes readers get turned off by those and drop the book before realizing he's been misleading you the whole time.
There is a lot about this book that I like. First, it's pleasantly readable. Second, he provides a lot of interesting anecdotes (and some really uninteresting ones, but I'll take the bad with the good). Finally, his research is really interesting! So I would totally recommend this book for the average person interested in the human history. I would also recommend it for the average person not interested in human history because it's still important to understand!
However (and this is a big however), I hate it when people perpetuate the notion that Watson and Crick literally "discovered" (yes, Sykes uses the word discovered) DNA's structure.
Sykes says several statements about Watson and Crick publishing their DNA structure that are either blatantly false or extremely misleading. That he mentions work done by other scientists, but only includes the names "Watson and Crick" heavily implies that Watson and Crick did work which it is common knowledge (and was common knowledge in 2001 when this book was published) that they did not do.
It's further confusing because he does a very thorough job describing the scientific chronology in blood group analysis (to name an example) by including the work of many teams of people around the world, even including a few very minor contributions. It makes me wonder why he was so thorough on that aspect, but not DNA.
Readers may be wondering, what's the big deal? That information is not fundamental to the story he's telling, it's just background knowledge! So Sykes got that part a little wrong, who cares?
The Big Deal is that in reading Sykes tell a story in a way that I know to be false, he discredits himself. I happen to be particularly knowledgable about the history around the discovery of DNA, but I know very little about most other discoveries/papers/scientists he talks about. Knowing he got one part wrong, what's the incentive to believe he got everything else right? How do I know he's telling the whole truth and doing justice to the correct people?
The answer is, I don't. Consequently I read the rest of the book with a totally different mindset - one of interest, but also suspicion. It didn't totally ruin the book for me, but it did make me less eager to read it.
With only the faint promise that at some point he will address the title, Sykes' narrative meanders through his explorations. He circles back on topics he addressed several chapters ago, sometimes providing new information that I wished he'd just included when it was brought up in the first place. This is especially apparent if you pay attention to where in the book he mentions his Polynesian research. He faithfully devotes a chapter to his history with their DNA, but then in subsequent chapters, when he makes a comparison back to his Polynesian research, he often includes a little bit of new Polynesian information, which I found annoying. On that note, he spends pages and pages explaining his reasoning process and I think he thinks he does a good job, but I found myself asking perfectly reasonable clarification questions that I kept waiting for him to address.
For example, I wasn't satisfied with his explanation for having seven as opposed to six or eight or even ten "clan mothers." For it being such a powerful result and the foundation for the book, he definitely skimps on the details and uses the idea of DNA "clusters", which I do understand, to back him up. I can infer that perhaps the pattern of mutations directs the timeline towards certain most probable break-points, but I wish he would have made it more explicit or gone into further detail on the method by which he grouped sequences.
Instead of concluding the book with seven dramatized (and in my opinion unnecessary) accounts of these seven women's lives, the pages would have been better served with a more thorough account of how he distinguished each woman from the others and precisely how his data revealed when and where they lived. For example, he brushes up on the idea that modern-day humans don't necessarily live where their direct ancestors lived, but he never addresses exactly how he factored that into his research at any point.
Finally, in the second to last chapter he introduces some awesome news: other researchers had discovered that, besides the seven women from whom the bulk of Europeans owe lineage, there are twenty-six additional clans that represent the rest of the world population! Wow! What blows my mind here is that the book title is clearly The Seven Daughters of Eve. 'Why the hell is that?' I ask, 'when Sykes clearly recognizes there to be thirty-three? Why, then, does Sykes title his book The Seven Daughters of Eve, and not The Thirty-Three Daughters of Eve?' There's a clear distinction here, in how he names the seven European ancestors to be Daughters of Eve, with the implication that the twenty-six other clans are not daughters of Eve. So in his view, Europeans are descended from Eve and the rest of the world is not? Yes, I get that there's a marketing element embedded in that decision, but again I question his ability to convey the full truth in a way that is not misleading. Titling the book The Seven Daughters of Eve is misleading and I hate that he did that. Consulting Figure 7 on page 275, we see no reason at all to suggest that anything sets the seven apart from the other twenty-six - their lineages are totally intermingling.
---
I know I didn't have to do this but I did so it's here and you can read it if you want.
"W+C felt sure [DNA] held the key to the chemical mechanism of heredity."
--Actually the American scientist Oswald Avery published that in 1944.
"There was a general lack of interest in this substance shown by most of their contemporaries."
--What he means is that most people were more interested in proteins than in DNA, but more interest in one thing does not imply lack of interest in another thing. There were tons of people working on DNA at the time, both in Europe and the US.
"They decided to have a crack at working out it's molecular structure, using...X-ray photography."
--Misleading - they dabbled in X-ray crystallography but weren't very good at it. They never created an X-ray photograph of DNA, ever.
"After many weeks... W+C suddenly found the [structure] that matched the X-ray."
--Again, misleading, they looked at Rosalind Franklin's Photo 51 X-ray photograph and stole parameters from her unpublished paper. They also consulted her and she told them that they had their base groups and phosphates pointing in the wrong directions. They couldn't figure it out on their own because they had no chemistry background.
"W+C had discovered that each molecule of DNA is made up of... a 'double helix'."
--False, they recognized the helix apparent in Photo 51 but were not the first to do so.
"W+C realized that the only way two strands of the double helix could fit together properly was if every 'A' on one strand is interlocked with a 'T' directly opposite."
--Actually the scientist Erlwin Chargaff figured that out in 1949.
There is a lot about this book that I like. First, it's pleasantly readable. Second, he provides a lot of interesting anecdotes (and some really uninteresting ones, but I'll take the bad with the good). Finally, his research is really interesting! So I would totally recommend this book for the average person interested in the human history. I would also recommend it for the average person not interested in human history because it's still important to understand!
However (and this is a big however), I hate it when people perpetuate the notion that Watson and Crick literally "discovered" (yes, Sykes uses the word discovered) DNA's structure.
Sykes says several statements about Watson and Crick publishing their DNA structure that are either blatantly false or extremely misleading. That he mentions work done by other scientists, but only includes the names "Watson and Crick" heavily implies that Watson and Crick did work which it is common knowledge (and was common knowledge in 2001 when this book was published) that they did not do.
It's further confusing because he does a very thorough job describing the scientific chronology in blood group analysis (to name an example) by including the work of many teams of people around the world, even including a few very minor contributions. It makes me wonder why he was so thorough on that aspect, but not DNA.
Readers may be wondering, what's the big deal? That information is not fundamental to the story he's telling, it's just background knowledge! So Sykes got that part a little wrong, who cares?
The Big Deal is that in reading Sykes tell a story in a way that I know to be false, he discredits himself. I happen to be particularly knowledgable about the history around the discovery of DNA, but I know very little about most other discoveries/papers/scientists he talks about. Knowing he got one part wrong, what's the incentive to believe he got everything else right? How do I know he's telling the whole truth and doing justice to the correct people?
The answer is, I don't. Consequently I read the rest of the book with a totally different mindset - one of interest, but also suspicion. It didn't totally ruin the book for me, but it did make me less eager to read it.
With only the faint promise that at some point he will address the title, Sykes' narrative meanders through his explorations. He circles back on topics he addressed several chapters ago, sometimes providing new information that I wished he'd just included when it was brought up in the first place. This is especially apparent if you pay attention to where in the book he mentions his Polynesian research. He faithfully devotes a chapter to his history with their DNA, but then in subsequent chapters, when he makes a comparison back to his Polynesian research, he often includes a little bit of new Polynesian information, which I found annoying. On that note, he spends pages and pages explaining his reasoning process and I think he thinks he does a good job, but I found myself asking perfectly reasonable clarification questions that I kept waiting for him to address.
For example, I wasn't satisfied with his explanation for having seven as opposed to six or eight or even ten "clan mothers." For it being such a powerful result and the foundation for the book, he definitely skimps on the details and uses the idea of DNA "clusters", which I do understand, to back him up. I can infer that perhaps the pattern of mutations directs the timeline towards certain most probable break-points, but I wish he would have made it more explicit or gone into further detail on the method by which he grouped sequences.
Instead of concluding the book with seven dramatized (and in my opinion unnecessary) accounts of these seven women's lives, the pages would have been better served with a more thorough account of how he distinguished each woman from the others and precisely how his data revealed when and where they lived. For example, he brushes up on the idea that modern-day humans don't necessarily live where their direct ancestors lived, but he never addresses exactly how he factored that into his research at any point.
Finally, in the second to last chapter he introduces some awesome news: other researchers had discovered that, besides the seven women from whom the bulk of Europeans owe lineage, there are twenty-six additional clans that represent the rest of the world population! Wow! What blows my mind here is that the book title is clearly The Seven Daughters of Eve. 'Why the hell is that?' I ask, 'when Sykes clearly recognizes there to be thirty-three? Why, then, does Sykes title his book The Seven Daughters of Eve, and not The Thirty-Three Daughters of Eve?' There's a clear distinction here, in how he names the seven European ancestors to be Daughters of Eve, with the implication that the twenty-six other clans are not daughters of Eve. So in his view, Europeans are descended from Eve and the rest of the world is not? Yes, I get that there's a marketing element embedded in that decision, but again I question his ability to convey the full truth in a way that is not misleading. Titling the book The Seven Daughters of Eve is misleading and I hate that he did that. Consulting Figure 7 on page 275, we see no reason at all to suggest that anything sets the seven apart from the other twenty-six - their lineages are totally intermingling.
---
I know I didn't have to do this but I did so it's here and you can read it if you want.
"W+C felt sure [DNA] held the key to the chemical mechanism of heredity."
--Actually the American scientist Oswald Avery published that in 1944.
"There was a general lack of interest in this substance shown by most of their contemporaries."
--What he means is that most people were more interested in proteins than in DNA, but more interest in one thing does not imply lack of interest in another thing. There were tons of people working on DNA at the time, both in Europe and the US.
"They decided to have a crack at working out it's molecular structure, using...X-ray photography."
--Misleading - they dabbled in X-ray crystallography but weren't very good at it. They never created an X-ray photograph of DNA, ever.
"After many weeks... W+C suddenly found the [structure] that matched the X-ray."
--Again, misleading, they looked at Rosalind Franklin's Photo 51 X-ray photograph and stole parameters from her unpublished paper. They also consulted her and she told them that they had their base groups and phosphates pointing in the wrong directions. They couldn't figure it out on their own because they had no chemistry background.
"W+C had discovered that each molecule of DNA is made up of... a 'double helix'."
--False, they recognized the helix apparent in Photo 51 but were not the first to do so.
"W+C realized that the only way two strands of the double helix could fit together properly was if every 'A' on one strand is interlocked with a 'T' directly opposite."
--Actually the scientist Erlwin Chargaff figured that out in 1949.