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OMG, OMG, OMG!The ending of this book truly blew my mind. I was completely caught off guard, not seeing it coming from a mile away. I had postponed reading this series for such a long time because the idea of a women's murder club seemed absurd. However, it turned out to be incredibly good. Boxer and the women are intelligent, sassy, and possess all the qualities I could ever desire in a group of characters.One of my favorite quotes from the book is from Claire, the coroner: "I'm in shape. Round is a shape." Each of the women has her own unique attributes, but I especially love their senses of humor and excellent detective skills. I have to admit that Claire is probably my favorite. Her insights as a doctor who couldn't heal really hit home for me as a medical professional.The killer in this book is another Patterson masterpiece. I swear the man must have some sort of twisted mind. The murderer's words, "What is the worst thing that anyone has ever done? Had he done it? Not yet....not quite yet," send shivers down my spine. Sex crimes always make me uncomfortable, and these particular ones were especially disturbing to the detectives. And oh my, the twist at the end made everything even worse.The plot itself is fascinating. A killer is targeting newly married brides and grooms and leaving them in extremely humiliating situations. What is the connection? What could be motivating this person? We are introduced to Boxer, then the reporter, then the coroner, and finally the assistant DA. As they compare their insider notes to try to solve the case and catch this sick individual, the women's murder club is born.One thing I always do is analyze any medical details in books to see if they are accurate. Patterson, however, does his research well. I can't find any flaws in his description of Neglis and the exhausting treatment that comes with some chronic conditions. I wish other authors would take the time to do their medical research so that they don't sound ridiculous.I'm not very good at writing summaries, but I wholeheartedly recommend giving these books a try. Starting this series made me think about detectives in general and the arcs they follow. After 20 years and 20 books, where will these characters be? Boxer started out as a hot mess on the verge of suicide, and I initially groaned. But as I watched her form bonds and grow, I became more invested in her story. So her arc going forward will be about putting her life back together and moving forward, and that's okay. While I do prefer detectives who have their lives in order, there's something interesting about a train wreck detective as well.I give 1st to Die a full five stars and another round of applause to Patterson for creating yet another completely messed up psychopath. :O