While one may not necessarily concur with Penrose's perspectives regarding the ultimate connections between mathematics, physics, and reality, I firmly believe that it is worthwhile to take his views seriously. This book is truly remarkable in that it caters to a wider audience, yet Penrose does not shy away from presenting the mathematical aspects. For a layperson, I envision that a great deal may be lost. However, I found Penrose's explanations surrounding the math to be generally quite good. Of course, they can only go so far.
I thoroughly enjoyed witnessing Penrose's take (in general, not just on spinors and twistors...) on various matters, ranging from basic mathematics to his views on the path of physics in the early 2000s. Penrose is an original thinker, and I highly appreciated the fact that he presented both traditional views and his own, while clearly indicating which ones were more speculative and which ones were more widely accepted within the general community. Given that 20 years have elapsed since the publication of this book, one might assume that the content it covers has become less relevant. In fact, most of it has remained relevant as it provides an overview, and we still have not made significant progress in the interpretations of quantum mechanics or in formulating a quantum-gravity theory. I'm not suggesting that no progress has been made, but it is astonishing how much of what Penrose said still holds true today.
Overall, it is a very interesting read. I did not attempt any of the exercises, but I would推测 that they do enhance the experience to some extent. If you are interested in a unique perspective on math and physics and how they have interacted, I believe it is a stimulating (albeit long) read.