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This book is just PACKED with serious implications about a number of topics. Let's just say that, if this guy is on the right track with his ideas about how paying conscious attention to specific thoughts, stimuli, etc., can actually affect the physical structure and circuitry of the brain, there are some tremendously important conclusions to be drawn about how the mind, consciousness, and the brain (and even the physical world outside the body) are related. Not to mention the conclusions that can be drawn about materialistic and existentialist philosophy! I'm not a huge fan of his dwelling on Buddhist philosophy-- it's relevant and clearly pushed him to explore the topic, but it doesn't add a lot to his theory. Not particularly well-written (a bit hard to follow the thread of his ideas, possibly because I took a 9-month break from reading it when I got to the middle....), and I would really like to see some current research on the topic, but this book was VERY much worth reading.