The death of Harry Angstrom is not unexpected in Rabbit at Rest. After all, the title of the novel alludes to Rabbit's outcome in a not-too-subtle way. The signs of Harry's demise are planted early and frequently. Even Rabbit himself, although never explicitly addressing it, seems to have a subconscious awareness to live in and for the moment, squeezing every bit of life he can. He knows that he and his ultimate fate will intersect sooner rather than later. The novel carries an undercurrent of personal entropy for Harry Angstrom. The systems of his life - social, emotional, and physical - are all slowly moving towards a terminal point. He decides that his best option is to ride out the growing chaos with a sardonic wit, an almost gleeful disregard for consequences, and the occasional plateful of bacon-wrapped scallops. This refusal to limit himself, despite the potential disastrous consequences for his life, gives Harry a modicum of the control he so desperately seeks. However, it also leaves him ill-prepared to face the harsh realities that come when this control can no longer be maintained. In the above passage, Updike shows the effects of the accumulated chaotic debris from this onslaught of upheaval on Harry's psyche, and the inherent fatalism that drives Rabbit to the rash behavior that ultimately leads to his death. Harry witnesses systems breaking down all around him, and the selfish joy he feels at his attempts to escape the degradation of his life fades into a lonely recognition of his own imminent mortality and the ultimate powerlessness he has over his situation.
The solitude that Harry experiences in the condo does nothing to improve his state of mind. The silence of the phone serves to emphasize his loneliness. Not only does he have no one in town to invite him to a social call or a round of golf, but he is also greeted with complete silence from the enraged Janice. Harry's active imagination cannot simply accept her reticence as a result of mixed emotions of anger and betrayal. In his first few days of hiding in the condo, he interprets her refusal to talk as a "definite statement. I'll never forgive you." Then, his chaotic imagination takes over, presenting images of her having "some accident…slipping in the bathtub or driving the Camry off the road….Police frogmen finding her drowned in the back seat." The lack of communication leaves no opportunity for him to gain control. For Harry, who constantly focuses on the disorder and failures of the world around him, not knowing how his wife feels, whether she is full of condemnation or leaning towards reconciliation, makes his psyche vulnerable to the harmful effects of the bad news he cannot seem to avoid. Thus, it is no surprise when "his cockiness ebbs," and he is left contemplating the sudden and inescapable doom that all men may face, whether it comes in the form of a bomb in a luggage hold or diseased and dying heart muscle. Updike presents him with a stream of uncontrollable events - hurricane Hugo and its aftermath, the failure of the government's health-care plan (which is now more important to him than ever), and the ever-present aviation disaster - that shatters the false confidence he had after his ill-advised basketball game. And, true to his nature, Harry responds to this loss of certainty with haphazard defiance, resulting in his second and fatal round of basketball.